Light Sheet Microscopy

Zeiss Light Sheet 7

Light Sheet Fluorescence Microscopy (LSFM) is an extremely powerful alternative to established fluorescence imaging techniques, especially for 3-D imaging within whole live organisms and large tissue explants. Ideal for fast and gentle imaging of whole living model organisms, tissues, and cells as they develop – over extended periods of time capable of imaging large optically cleared specimens in toto – with subcellular resolution. By selectively illuminating the observed optical section with a thin sheet of light, photo bleaching is reduced to a minimum, making light sheet microscopy ideal for nondestructive imaging of fragile samples over extended periods of time. Equipped with an incubation system with temperature and CO₂ control for long-term in vivo experiments.